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  1. Home
  2. Efficacy and Pain Guidelines
  3. Dental Pain Studies and Guidelines
  4. Non-Opioid Dental Pain Relief

Aleve®: a powerful non-opioid treatment for minor dental pain2

See results in new dental study: Aleve® was as effective* as hydrocodone plus acetaminophen (HYD+APAP) for pain, lasted longer, and was better tolerated2

*In hours 0 to 4 of a single-dose dental study of Aleve® (440 mg), HYD+APAP (10 mg + 650 mg), or placebo. Aleve® is indicated for minor aches and pains.2,3

Did you know that up to half of opioid prescriptions at dental visits are inconsistent with the guidelines on appropriate use of opioids?4 In response to the overuse of opioids, there is an increasing interest in the effectiveness of OTC NSAIDs in alleviating pain—to reduce the need for opioids.2 Aleve® is an OTC pain reliever indicated for temporary relief of minor aches and pains including arthritis pain, headache, muscular aches, and toothache.3

Click below to learn more about opioid overuse and misuse and why opioids are still a major crisis.5,6 And see how Aleve® compared with HYD+APAP for dental pain in the single-dose study.

SEE NEW DATA: ALEVE® VS HYD+APAP ›

THE US OPIOID CRISIS AND HOW NSAIDs LIKE ALEVE® CAN HELP2,7 ›

References: 1. Pain Medicine News. OTC NSAID Performs Better Than Opioid Combo Product in Wisdom Tooth Surgery. July 2022. Accessed August 18, 2022. https://www.painmedicinenews.com/Multimedia/Article/07-22/OTC-NSAID-Performs-Better-Than-Opioid-Combo-Product-in-Wisdom-Tooth-Surgery/67602. 2. Cooper SA, Desjardins PJ, Bertoch T, et al. Analgesic efficacy of naproxen sodium versus hydrocodone/acetaminophen in acute postsurgical dental pain: a randomized, double-blind, placebo-controlled trial. Postgrad Med. 2021. doi:10.1080/00325481.2021.2008180. 3. Aleve® Caplets. Drug facts. Bayer HealthCare; April 2018. 4. Suda K, Zhou J, Rowan S, et al. Overprescribing of opioids to adults by dentists in the U.S., 2011-2015. Am J Prev Med. 2020;58(4):473-486. doi:10.1016/j.amepre.2019.11.006 5. Manchikanti L, Singh A. Therapeutic opioids: a ten-year perspective on the complexities and complications of the escalating use, abuse, and nonmedical use of opioids. Pain Physician. 2008;11(2 Suppl):S63-S88. 6. Scholl L, Seth P, Kariisa M, Wilson N, Baldwin G. Drug and opioid-involved overdose deaths—United States, 2013-2017. MMWR Morb Mortal Wkly Rep. 2019;67(51-52):1419-1427. 7. Department of Health and Human Services. Determination that a public health emergency exists. October 26, 2017.

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