THE ONLY OTC ORAL
ANALGESIC BRAND THAT OFFERS
POWERFUL PAIN RELIEF FOR
UP TO 12 HOURS WITH ONE DOSE.* 

THE ONLY OTC ORAL ANALGESIC BRAND THAT OFFERS POWERFUL PAIN RELIEF FOR UP TO 12 HOURS WITH ONE DOSE.* 

SEE THE DIFFERENCE

SEE THE DIFFERENCE

Bottle of Aleve pain reliever

LONGER* LASTING RELIEF STARTS HERE

Aleve® targets pain caused by inflammation and provides up to 2x longer pain relief per dose compared to extra strength acetaminophen and ibuprofen*

*Based on minimum labeled dosing.

LONGER* LASTING RELIEF STARTS HERE

Aleve® targets pain caused by inflammation and provides up to 2x longer pain relief per dose compared to extra strength acetaminophen and ibuprofen*

*Based on minimum labeled dosing.

 

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TOP CHOICE

NSAIDs such as Aleve® are the preferred initial treatment for OA pain by major guidelines1,2

TOP CHOICE

NSAIDs such as Aleve® are the preferred initial treatment for OA pain by major guidelines1,2

LEARN MORE
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PROVEN STRENGTH3†

Up to 12 hours of powerful pain relief, backed by a growing body of evidence

PROVEN STRENGTH3†

Up to 12 hours of powerful pain relief, backed by a growing body of evidence

SEE DATA
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TRUSTED BRAND

Relieving pain for
over 30 years

TRUSTED BRAND

Relieving pain for
over 30 years

SEE SAFETY

 

OA = osteoarthritis.

†Based on a clinical study vs HYD+APAP during the first 4 hours after initial dosing.

References: 1. Kolasinski SL, Neogi T, Hochberg MC, et al. 2019 American College of Rheumatology/Arthritis Foundation guideline for the management of asteoarthritis of the hand, hip, and knee. Arthritis Care Res (Hoboken). 2020;72(2):149-162. doi:10.1002/acr.24131 2. Brophy RH, Fillingham YA. AAOS clinical practice guideline summary: management of osteoarthritis of the knee (nonarthroplasty). J Am Acad Orthop Surg. 2022;30(9):e721-e729. doi: 10.5435/JAAOS-D-21-01233. Accessed October 16, 2025. https://journals.lww.com/jaaos/Fulltext/2022/05010/AAOS_Clinical_Practice_Guideline_Summary_.10.aspx 3. Cooper SA, Desjardins PJ, Bertoch T, et al. Analgesic efficacy of naproxen sodium versus hydrocodone/acetaminophen in acute postsurgical dental pain: a randomized, double-blind, placebo-controlled trial. Postgrad Med. 2021. doi:10.1080 00325481.2021.2008180