NAPROXEN SODIUM STUDIES AND
PAIN GUIDELINES

Aleve® is an OTC pain reliever and fever reducer indicated for temporary relief of minor aches and pains, and the temporary reduction of fever. Many kinds of pain, including minor osteoarthritis (OA) pain, dental pain, and dysmenorrhea have been proven responsive to naproxen sodium, a long-lasting OTC NSAID and the primary ingredient in Aleve®, at nonprescription strengths.

Click below to learn more about the effectiveness of Aleve® in various pain states in clinical studies, including the recent Aleve® vs hydrocodone plus acetaminophen (HYD+APAP) study comparing a single-dose of each after dental surgery. This recent, single-dose dental study provides evidence for considering an OTC NSAID like Aleve® for minor dental pain.1

DENTAL PAIN ›

PRIMARY DYSMENORRHEA ›

OSTEOARTHRITIS PAIN ›

MUSCULOSKELETAL PAIN ›

ADDITIONAL CLINICAL MATERIALS ›

Reference: 1. Cooper SA, Desjardins PJ, Bertoch T, et al. Analgesic efficacy of naproxen sodium versus hydrocodone/acetaminophen in acute postsurgical dental pain: a randomized, double-blind, placebo-controlled trial. Postgrad Med. 2021. doi:10.1080/00325481.2021.2008180