RECOMMEND THE PAIN RELIEVING POWER OF ALEVE® WITH CONFIDENCE

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SAFETY PROFILE

  • Adverse events for OTC Aleve® were not significantly different than placebo, as shown in a large meta-analysis of pooled safety data from clinical trials1 LINK TO STUDY
  • In a separate analysis, adverse event rates for naproxen/naproxen sodium were shown to be no worse than placebo, with 83% of patients treated with naproxen/naproxen sodium reporting no adverse events2
    The most commonly reported adverse events were headache, nausea, and somnolence LINK TO STUDY
  • Very rare (<0.01%) incidence of serious or life-threatening hepatic adverse events when taken as directed, as shown in combined reporting from clinical trial data3
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RELIEVING PAIN FOR OVER 30 YEARS

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168 MILLION PATIENTS USED ALEVE® PRODUCTS IN THE LAST YEAR ALONE3

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AN ORTHOPEDIC SURGEON-RECOMMENDED OTC BRAND FOR MINOR ARTHRITIC PAIN

 

Aleve Yellow Line
Aleve Yellow Line

References 

  1. Kyeremateng K, Troullos E, Paredes-Diaz A. Safety of naproxen compared with placebo, ibuprofen and acetaminophen: a pooled analysis of eight multiple-dose, short-term, randomized controlled studies. Curr Med Res Opin. 2019;35(10):1671-1676. doi:10.1080/03007995.2019.1612338

  2. DeArmond B, Francisco CA, Lin J-S, et al. Safety profile of over-the-counter naproxen sodium. Clin Ther. 1995;17(4): 587-601. doi:10.1016/0149-2918(95)80036-0

  3. Data on file.