Aleve® FAQ | Aleve® HCP

FREQUENTLY ASKED QUESTIONS

You and your patients have questions about Aleve®. We have answers.

Cardiovascular

The labeling for Aleve® is consistent with over-the-counter (OTC) nonsteroidal anti-inflammatory drug (NSAID) labeling and includes a warning designed to inform consumers that “when using this product, the risk of heart attack or stroke may increase if you use more than directed or for longer than directed.”1

Ask a doctor before use if

  • under a doctor's care for any serious condition
  • taking aspirin for heart attack or stroke, because naproxen may decrease this benefit of aspirin
  • taking any other drug

Heart attack and stroke warning: NSAIDs, except aspirin, increase the risk of heart attack, heart failure, and stroke. These can be fatal. The risk is higher if you use more than directed or for longer than directed.

References:

  1. Aleve® Label.

Dental

Dysmenorrhea

First-line Treatment for Acute Pain

Many professional organizations recommend NSAIDs like naproxen sodium, the active ingredient in ALEVE®, as a first-line treatment for acute pain. Some of these organizations include:

  • American Dental Association
  • American Association of Oral and Maxillofacial Surgeons
  • American College of Gynecology
  • American Academy of Orthopaedic Surgeons
  • American College of Rheumatology
  • Osteoarthritis Research Society International
  • American College of Physicians

To view the the full recommendations, visit each of the organizations' websites.

Gastrointestinal

The labeling for Aleve® is consistent with over-the-counter (OTC) nonsteroidal anti-inflammatory drug (NSAID) labeling and a “Stomach Bleeding Warning” designed to inform consumers that the product contains an NSAID, which “may cause severe stomach bleeding.”1

  • The warning informs consumers that the risk of stomach bleeding is higher if: they are age 60 or older, have had stomach ulcers or bleeding problems, take a blood thinning (anticoagulant) or steroid drug, take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen or others), have three or more alcoholic drinks every day while using the product, or take more or for a longer time than directed.1
  • Consumers are advised to ask a doctor before use if: the stomach bleeding warning applies to them or if they have a history of stomach problems such as heartburn.1
  • Consumers are advised to stop use and ask a doctor if: they experience any of the following signs of stomach bleeding, including feeling faint, vomiting blood, bloody or black stools, or stomach pain that does not get better.1

The risk of GI bleeding with NSAID use is dose-dependent on and impacted by the duration of use.2 The minimum effective dose for the shortest duration of NSAID use is generally recommended to minimize undesirable effects including GI side effects.

References:

  1. Aleve® Label.
  2. Tarone 2004.
  3. Bansal- JCLinPharmacol 2001.
  4. Aisen 2007.

If you have additional questions that are not answered here, or in other sections of the FAQ portion of the website, please feel free to contact us.

General

Following are answers to questions about the ingredients and dosing of ALEVE®. If you have additional questions that are not answered here, please feel free to contact us.

Liver

The labeling for Aleve® is consistent with over-the-counter (OTC) nonsteroidal anti-inflammatory drug (NSAID) labeling and contains a warning for patients with liver cirrhosis to consult with their doctors before use.1

References:

  1. Aleve® Label.
  2. Data on file.

If you have additional questions that are not answered here, or in other sections of the FAQ portion of the website, please feel free to contact us.

NSAID Allergy Alert

The labeling for Aleve® is consistent with over-the-counter (OTC) nonsteroidal anti-inflammatory drug (NSAID) labeling with regards to the "Allergy Alert" and states that naproxen sodium may cause a severe allergic reaction, especially in people allergic to aspirin. Symptoms may include hives, facial swelling, asthma (wheezing), shock, skin reddening, rash and blisters.1

References:

  1. Aleve® Label.
  2. Data on file.

If you have additional questions that are not answered here, or in other sections of the FAQ portion of the website, please feel free to contact us.

Renal

The labeling for Aleve® is consistent with over-the-counter (OTC) nonsteroidal anti-inflammatory drug (NSAID) labeling, which contains instructions for patients with kidney disease to consult with their doctor before use.1

References:

  1. Aleve® Label.
  2. Data on file.
  3. Curhan 2004.

If you have additional questions that are not answered here, or in other sections of the FAQ portion of the website, please feel free to contact us.