General Information About Aleve
What is Aleve?
Aleve is an over-the-counter (OTC), nonsteroidal, anti-inflammatory (NSAID) pain reliever that provides temporary relief of minor aches and pains from a variety of conditions. It also temporarily reduces fever.
What is the active ingredient in Aleve?
Naproxen sodium, 220 mg. Aleve contains 200 mg of naproxen and 20 mg of sodium (salt).
What is Aleve used for?
Temporarily relieves aches and pains due to: Temporarily reduces fever
What is the advantage of using Aleve over other pain relievers?
  • Aleve has less frequent dosing and fewer pills than other common, over-the-counter pain relievers when pain persists. Just 2 Aleve can provide pain relief that can last all day. Each Aleve pill has the strength to last 12 hours.
  • Compare it! Based on minimum label dosing for 24 hours, you could take 6 Extra-Strength Tylenol®* or 4 Advil®† to get all-day relief if pain persists. Aleve can relieve pain all day with just 2 pills. Each Aleve pill has the strength to last 12 hours.
  • Aleve is available without a prescription, so it’s easy to get pain relief that can last all day.
*Tylenol® is a registered trademark of Johnson & Johnson
Advil® is a registered trademark of Wyeth, LLC.
How does Aleve work to relieve pain?
  • Aleve works by temporarily blocking the body’s production of naturally occurring chemicals called prostaglandins.
  • Prostaglandins play a direct role in pain.
Is Aleve an anti-inflammatory?
Aleve belongs to a class of drugs known as Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) but is not indicated as an anti-inflammatory.
What is the difference between a tablet and a caplet?
The only difference is in the shape. Both the Aleve tablets and caplets contain the same amount of medicine. Some people find that an oval caplet is easier to swallow, while others prefer the round tablet shape.
How is Aleve different from the prescription drug Naprosyn®?
  • Naprosyn contains more naproxen per pill than Aleve and is only available with a prescription.
  • Naprosyn is indicated for treatment of acute pain, chronic (continuing) pain and inflammatory conditions under a doctor’s supervision.
  • Aleve contains naproxen sodium and is indicated for temporary relief of minor aches and pains and temporary reduction of fever.
  • Aleve is available over-the-counter, so you can get long-lasting pain relief without a prescription.
Naprosyn® is a registered trademark of SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED CORPORATION
How is Aleve different from the prescription drug Anaprox®?
  • Aleve is the nonprescription version of the prescription drug Anaprox.
  • Anaprox contains more naproxen sodium per pill than Aleve and is only available with a prescription.
  • Anaprox is indicated for treatment of acute pain, chronic (continuing) pain and inflammatory conditions under a doctor’s supervision.
  • Aleve contains naproxen sodium and is indicated for temporary relief of minor aches and pains and reduction of fever.
  • Aleve is available over-the-counter, so you can get long-lasting pain relief without a prescription.
Anaprox® is a registered trademark of SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED CORPORATION
Ingredients in Aleve
Does Aleve contain aspirin?
  • No. Aleve does not contain aspirin.
  • Aleve should not be taken with aspirin, aspirin-containing products or any other pain reliever/fever reducer, unless your doctor has instructed you to do so.
  • Naproxen sodium may cause a severe allergic reaction, especially in people allergic to aspirin. Symptoms may include hives, facial swelling, asthma (wheezing), shock, skin reddening, rash or blisters. If an allergic reaction occurs, stop use and seek medical help right away.
Does Aleve contain gluten?
We do not add any gluten to our products. However, we cannot guarantee that they are 100% gluten-free, as this product is produced in a facility that manufactures or packages other items which may contain gluten.
Does Aleve contain ibuprofen?
  • No. Aleve does not contain ibuprofen.
  • Aleve should not be taken with ibuprofen or any other pain reliever, unless your doctor has instructed you to do so.
  • Do not take Aleve if you have ever had an allergic reaction to any other pain reliever/fever reducer.
Does Aleve contain acetaminophen?
  • No. Aleve does not contain acetaminophen.
  • Aleve should not be taken with acetaminophen or any other pain reliever, unless your doctor has instructed you to do so.
  • Do not take Aleve if you have ever had an allergic reaction to any other pain reliever/fever reducer.
Does Aleve contain sodium (salt)?
  • Each Aleve tablet, caplet, gelcap and liquid gel capsule contains 20 mg of sodium and is classified as "low sodium" under FDA guidelines.
  • The active ingredient in Aleve (naproxen) is combined with sodium so it dissolves faster.
Does Aleve contain caffeine?
No. Aleve does not contain caffeine.
Aleve Dosage
What are the daily and maximum doses for adults?
  • Take one tablet, caplet, gelcap, or liquid gel every 8 to 12 hours while symptoms last. For the first dose, you may take 2 tablets, caplets, gelcaps or capsules within the first hour.
  • Do not exceed 2 tablets, caplets, or gelcaps, or liquid gels in any 8- to 12-hour period, and do not exceed 3 tablets, caplets or gelcaps, or liquid gels in a 24-hour period. The smallest effective dose should be used. Drink a full glass of water with each dose.
  • Do not take longer than 10 consecutive days for pain or 3 days for fever, unless directed by a doctor.
What’s the dose for children under 12?
Do not give this product to children under age 12, except under the advice and supervision of a doctor.
How many days can I take Aleve?
Do not take longer than 10 consecutive days for pain or 3 days for fever, unless directed by a doctor.
Aleve Labeling Information & Usage
What are some of Aleve’s possible side effects?
  • Common side effects seen with Aleve are abdominal pain, dizziness, headache, heartburn, nausea and light-headedness. More serious, though rare, effects seen with Aleve include severe allergic reactions. This product contains an NSAID, which may cause severe stomach bleeding.
  • If you have experienced a side effect, you should speak with your healthcare provider about continuing to take Aleve.
  • When taken as directed on the label, Aleve is a safe and effective pain reliever. Since its introduction as an over-the-counter product in 1994, Aleve has been used by millions of people as a safe and effective pain reliever.
Can Aleve cause allergic reactions?
Yes. If you have ever had hives, facial swelling, asthma (wheezing), shock, rash, skin reddening, or blisters after taking a pain reliever or fever reducer, do not take Aleve. You may have a serious reaction. If an allergic reaction occurs on Aleve, stop use and seek medical help right away.
Can Aleve be taken if I have high blood pressure?
Your doctor best understands your overall health. Talk with him or her to determine if Aleve is appropriate for you.
Can Aleve be taken with high blood pressure medication?
Aleve can interact with some blood pressure medications, so talk to your doctor to determine whether Aleve is appropriate for you.
Can Aleve be taken with blood thinners such as Coumadin?
If you are taking any other drug, talk to a doctor before use to determine whether Aleve is appropriate for you.
Can Aleve be taken with other over-the-counter medications or prescription medications?
  • If you are taking any other drug, talk to a doctor or pharmacist before use to determine whether Aleve is appropriate for you.
  • Interactions from using 2 drugs at the same time are possible. (Interactions are the effects that result from using 2 drugs at the same time; one may make the other less effective or cause mild to serious side effects.)
Can Aleve be taken with other over-the-counter pain relievers such as aspirin, Tylenol® or Advil®?
No pain reliever, including Aleve, should be taken while using any of these products, unless directed to do so by your doctor. If you are taking aspirin on a daily basis, check with your doctor before using any other pain relief product.
Can I drink alcoholic beverages (wine, beer or liquor) while I’m taking Aleve?
This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you have 3 or more alcoholic drinks every day while using this product.
Should I take Aleve with food or liquid?
A full glass of water is required. Take with food or milk if an upset stomach occurs.
Is it okay to take Aleve before or after surgery?
Discuss this issue with your doctor to get the answer that’s right for your needs. Only he or she is best qualified to answer this question.
Is it alright to use Aleve while pregnant or nursing?
If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use naproxen sodium during the last 3 months of pregnancy, unless specifically directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery.
Can I take Aleve if I have diabetes?
Speak with your doctor before adding any drug to your current medication(s).
The package says my Aleve has expired – can I still use it?
It is not recommended to use any over the counter product beyond the labeled expiration date. Like all drugs, Aleve can deteriorate over time and not be as effective once it is past its expiration.
Can they be chewed/crushed/cut in half?
While we recommend that the product be swallowed whole with a full glass of water, there is no harm in chewing or crushing the tablet. Regardless of how it is taken, it is recommended that it be taken with a full glass of water. The Liquid Gels should not be cut or crushed and should be swallowed whole with a full glass of water.
Aleve Packaging
What are Aleve Arthritis Caps?
Has the Aleve Arthritis Cap package been approved by the Arthritis Foundation®?
Yes. The Easy Open Arthritis Cap and Soft Grip Arthritis Cap were approved and have received the Arthritis Foundation’s Ease-of-Use Commendation. The Soft Grip Arthritis Cap also passed the strict guidelines and test protocol of the Consumer Product Safety Commission for child-resistant packaging.
Are Aleve bottles recyclable?
  • Yes, our Aleve bottles are HDPE (high-density polyethylene and polystyrene) plastic. If you do wish to recycle the Aleve bottle, it is classified as a mixed plastics code “7.”
  • Our non-arthritis Aleve cap is recyclable and made of polypropylene plastic. It is classified as a code “5.”
  • Our new Aleve Easy Open Arthritis Cap is recyclable and made of polypropylene plastic. It is classified as a mixed plastics code “7.”
Why do some Aleve bottles have a fold-out label?
Some of our bottles have a fold-out label that provides more room to print directions and warnings. The label also uses a larger print size so important information can be more easily read.
What if I have other questions or comments about Aleve?
Aleve encourages you to contact us in the U.S. via email or our toll-free telephone number: 1-800-395-0689.
Aleve PM Product FAQs
What is Aleve PM?
Aleve PM is the first and only over-the-counter (OTC) PM product with the 12-hour pain relieving strength of Aleve plus a sleep aid. Each caplet combines the sleep aid, diphenhydramine HCl (25 mg) with the pain reliever naproxen sodium (220 mg), a nonsteroidal anti-inflammatory drug, to provide relief from occasional sleeplessness associated with minor aches and pains. It can help you fall asleep and stay asleep.
What are the active ingredients in Aleve PM?
Each caplet contains naproxen sodium, 220 mg, which can provide up to 12-hours of pain relief, and diphenhydramine HCl, 25 mg, which is a sleep aid.
What is Aleve PM used for?
Aleve PM should be used for: 1) occasional sleeplessness associated with minor aches and pains, and 2) help falling asleep and staying asleep.
How does Aleve PM work?
Aleve PM can help you fall asleep and stay asleep with less pain for a good night’s rest. The naproxen sodium (220 mg) in Aleve PM works by temporarily blocking the body's production of naturally occurring chemicals called prostaglandins. Prostaglandins play a direct role in pain. Naproxen sodium has the strength to provide up to 12 hours of pain relief. The diphenhydramine HCl in Aleve PM acts as a sleep aid.
How is Aleve PM different from regular Aleve?
Aleve PM contains the same pain reliever found in Aleve (naproxen sodium), but also has a sleep aid (diphenhydramine HCl) so you can stay asleep with less pain and have a good night’s rest.
Is Aleve PM an anti-inflammatory?
Each Aleve PM caplet combines the pain reliever naproxen sodium (220 mg), part of a class of drugs known as Nonsteroidal Anti-Inflammatory Drugs (NSAIDs), with the sleep aid diphenhydramine HCl (25 mg). You should consult your doctor if you have questions about whether Aleve PM is right for you.
Is Aleve PM a sleep aid?
Each Aleve PM caplet combines the sleep aid diphenhydramine HCl (25 mg) with the pain reliever naproxen sodium (220 mg) to provide relief from occasional sleeplessness when associated with minor aches and pains. It can help you fall asleep and stay asleep.
Will Aleve PM treat allergy symptoms?
No, Aleve PM is not indicated to treat allergy symptoms. Although Aleve PM contains diphenhydramine HCl, which can be used as both an anti-histamine and a sleep aid, it is indicated as a sleep aid in Aleve PM. Aleve PM should be used according to the labeled directions.
What are the benefits of Aleve PM?
Aleve PM can provide long-lasting relief from occasional sleeplessness associated with back, muscle or minor arthritis pain. Aleve PM is the first and only over-the-counter (OTC) PM product with the 12-hour pain relieving strength of Aleve plus a sleep aid so you can fall asleep easily and wake up with less pain.
Has Aleve PM been found to be safe?
Yes, Aleve PM was found to be safe in clinical trials. Aleve PM is indicated for occasional sleeplessness associated with minor aches and pain. Aleve PM is safe and effective when used as directed.
What is the safety history of the ingredients in Aleve PM?
The two active ingredients in Aleve PM, naproxen sodium and diphenhydramine HCl, have a long history of being safe and effective when used as directed. Naproxen sodium has been used for over 30 years; diphenhydramine HCl has been used for over 60 years.
Is Aleve PM as safe as Aleve?
Both products were approved by the FDA as safe and efficacious when used according to labeled directions.
What are the possible side effects of Aleve PM?
In clinical studies, the most common side effects were nausea, headaches, dizziness, and vomiting. Refer to the Aleve PM drug facts label and use as directed.

As with all NSAIDs, this product contains a stomach bleeding warning and may cause severe stomach bleeding.

As with all NSAIDS, this product contains an allergy warning. Naproxen Sodium may cause a severe allergic reaction, especially in people allergic to aspirin. If an allergic reaction occurs, consumers should stop use and seek medical help right away.

If you have experienced any side effect, you should speak with your healthcare provider about continuing to take Aleve PM. See package labeling for complete information and warnings.
Can/Should Aleve PM be taken with food?
If stomach upset occurs, Aleve PM can be taken with food or milk. If taken with food, the product may take longer to work.
Can you take Aleve with Aleve PM?
Aleve PM should not be taken at the same time as Aleve. In a 24-hour period, you can take Aleve PM at bedtime and one Aleve 12 hours before or after the Aleve PM dose.
Can you take Aleve PM during the day?
It is not recommended to take Aleve PM during the day if you are not planning to sleep, because it contains a sleep aid, which causes drowsiness.
What if you take more Aleve PM caplets than directed within a 24-hour period?
It is not recommended to take more than two caplets within 24 hours.
Taking more than directed can cause serious health problems. In case of overdose, get medical help or contact a Poison Control Center right away.
Is Aleve PM habit-forming?
The FDA has approved Aleve PM as safe and effective when used as directed. Aleve PM contains a non-habit forming sleep-aid, diphenhydramine HCl.
Aleve-D Product FAQs
How does Aleve-D work?
Aleve-D contains naproxen sodium and extended release pseudoephedrine. Naproxen sodium is an effective long-acting analgesic that relieves headaches, body aches and pains, and fever that may result from a cold. The pseudoephedrine HCL in Aleve-D is an extended release nasal decongestant and works by promoting sinus drainage, decreasing swelling of the nasal mucosa, and reducing sinus pressure.
How does Aleve-D last up to 12 hours?
Aleve-D lasts up to 12 hours because naproxen sodium is inherently a long-lasting pain reliever and the pseudoephedrine component is specially formulated to provide extended relief for up to 12 hours with just one pill.
Is Aleve-D considered a "non-drowsy" formula?
Yes. Aleve-D does not contain an anti-histamine and is therefore considered to be "non-drowsy."
What are the active ingredients in Aleve-D?
There are two active ingredients: naproxen sodium 220 mg and extended release pseudoephedrine HCL 120 mg.
What is naproxen sodium?
Naproxen sodium is an analgesic and is indicated for the temporary relief of minor aches and pains due to the common cold, for the temporary reduction of fever, and for the relief of other types of mild to moderate pain.
Can Aleve and Aleve-D be taken at the same time?
No, the two products should not be taken at the same time. The total daily limit for naproxen sodium (660 mg) must be observed.
What are the possible side effects of Aleve-D?
  • Common side effects seen with Aleve-D are: dizziness, drowsiness, headache, lightheadedness, nausea, nervousness, palpitations, sleeplessness and vomiting. When side effects of Aleve-D do occur, in most cases, they are minor and do not require medical attention.
  • More serious, though rare effects seen with Aleve-D include severe allergic reactions, gastrointestinal ulcers and gastrointestinal bleeding. If an allergic reaction or bleeding event occurs, stop use and seek medical help right away.
  • If you have experienced any side effect, you should speak with your healthcare provider about continuing to take Aleve-D. See package labeling for complete information and warnings.
Where can I find Aleve-D for purchase?
  • Click here to use the Product Locator tool at BayerCare.com to find an Aleve-D product in a store near you.
  • Aleve-D is available behind the pharmacy counter without a prescription.
General Sinus & Cold FAQs
What is nasal congestion?
Nasal congestion can result from inflammation of the lining of the nasal passages. It is caused by a swelling of the blood vessels, excess fluid in the tissues, and an increased secretion of mucus.
What causes nasal congestion?
Congestion of the membrane lining of the nasal passages results most commonly from upper respiratory infections caused by a wide variety of viruses, for example the common cold. It may also be caused by pollens and other irritants in the air.
What is sinus pressure?
Pressure in the sinuses results from an accumulation of fluids and a swelling of the blood vessels in the mucus membrane lining of the sinuses.
What is the difference between having a cold and having sinus pressure?
Sinus pressure may be one of the many symptoms of the common cold. In addition to sinus pressure, symptoms of a cold may include coughing, sneezing, nasal congestion, headache, minor body aches and fever.
How long will my cold symptoms last?
A cold usually lasts approximately 7 days. Clinical signs and symptoms vary from person to person and may include: sore throat, sinus pressure, minor body aches, headache, nasal and sinus congestion, and occasionally a slight fever. Treatment should temporarily relieve your cold symptoms.
How can I prevent a cold?
Handwashing is the most effective way to prevent colds. If possible, one should avoid close, prolonged exposure to persons who have colds. Daily diets should include foods such as fresh, dark-colored fruits and vegetables, which are rich in antioxidants that help support the immune system. Viruses causing the cold can survive hours outside the nasal passages on inanimate objects and skin. Therefore, cleaning household surfaces with antiviral disinfectant might help prevent the spread of infection.
Is my cold contagious?
Yes. Colds are caused by more than 200 different viruses. These viruses are spread by person-to-person contact through contaminated secretions on the fingers and hands, and through particles in the air from sneezing and coughing.
What is Aleve?
Aleve is an over-the-counter (OTC), nonsteroidal, anti-inflammatory (NSAID) pain reliever that provides temporary relief of minor aches and pains from a variety of conditions. It also temporarily reduces fever.
What is the active ingredient in Aleve?
Naproxen sodium, 220 mg. Aleve contains 200 mg of naproxen and 20 mg of sodium (salt).
What is Aleve used for?
Temporarily relieves aches and pains due to: Temporarily reduces fever
What is the advantage of using Aleve over other pain relievers?
  • Aleve has less frequent dosing and fewer pills than other common, over-the-counter pain relievers when pain persists. Just 2 Aleve can provide pain relief that can last all day. Each Aleve pill has the strength to last 12 hours.
  • Compare it! Based on minimum label dosing for 24 hours, you could take 6 Extra-Strength Tylenol®* or 4 Advil®† to get all-day relief if pain persists. Aleve can relieve pain all day with just 2 pills. Each Aleve pill has the strength to last 12 hours.
  • Aleve is available without a prescription, so it’s easy to get pain relief that can last all day.
*Tylenol® is a registered trademark of Johnson & Johnson
Advil® is a registered trademark of Wyeth, LLC.
How does Aleve work to relieve pain?
  • Aleve works by temporarily blocking the body’s production of naturally occurring chemicals called prostaglandins.
  • Prostaglandins play a direct role in pain.
Is Aleve an anti-inflammatory?
Aleve belongs to a class of drugs known as Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) but is not indicated as an anti-inflammatory.
What is the difference between a tablet and a caplet?
The only difference is in the shape. Both the Aleve tablets and caplets contain the same amount of medicine. Some people find that an oval caplet is easier to swallow, while others prefer the round tablet shape.
How is Aleve different from the prescription drug Naprosyn®?
  • Naprosyn contains more naproxen per pill than Aleve and is only available with a prescription.
  • Naprosyn is indicated for treatment of acute pain, chronic (continuing) pain and inflammatory conditions under a doctor’s supervision.
  • Aleve contains naproxen sodium and is indicated for temporary relief of minor aches and pains and temporary reduction of fever.
  • Aleve is available over-the-counter, so you can get long-lasting pain relief without a prescription.
Naprosyn® is a registered trademark of SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED CORPORATION
How is Aleve different from the prescription drug Anaprox®?
  • Aleve is the nonprescription version of the prescription drug Anaprox.
  • Anaprox contains more naproxen sodium per pill than Aleve and is only available with a prescription.
  • Anaprox is indicated for treatment of acute pain, chronic (continuing) pain and inflammatory conditions under a doctor’s supervision.
  • Aleve contains naproxen sodium and is indicated for temporary relief of minor aches and pains and reduction of fever.
  • Aleve is available over-the-counter, so you can get long-lasting pain relief without a prescription.
Anaprox® is a registered trademark of SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED CORPORATION
Does Aleve contain aspirin?
  • No. Aleve does not contain aspirin.
  • Aleve should not be taken with aspirin, aspirin-containing products or any other pain reliever/fever reducer, unless your doctor has instructed you to do so.
  • Naproxen sodium may cause a severe allergic reaction, especially in people allergic to aspirin. Symptoms may include hives, facial swelling, asthma (wheezing), shock, skin reddening, rash or blisters. If an allergic reaction occurs, stop use and seek medical help right away.
Does Aleve contain gluten?
We do not add any gluten to our products. However, we cannot guarantee that they are 100% gluten-free, as this product is produced in a facility that manufactures or packages other items which may contain gluten.
Does Aleve contain ibuprofen?
  • No. Aleve does not contain ibuprofen.
  • Aleve should not be taken with ibuprofen or any other pain reliever, unless your doctor has instructed you to do so.
  • Do not take Aleve if you have ever had an allergic reaction to any other pain reliever/fever reducer.
Does Aleve contain acetaminophen?
  • No. Aleve does not contain acetaminophen.
  • Aleve should not be taken with acetaminophen or any other pain reliever, unless your doctor has instructed you to do so.
  • Do not take Aleve if you have ever had an allergic reaction to any other pain reliever/fever reducer.
Does Aleve contain sodium (salt)?
  • Each Aleve tablet, caplet, gelcap and liquid gel capsule contains 20 mg of sodium and is classified as "low sodium" under FDA guidelines.
  • The active ingredient in Aleve (naproxen) is combined with sodium so it dissolves faster.
Does Aleve contain caffeine?
No. Aleve does not contain caffeine.
What are the daily and maximum doses for adults?
  • Take one tablet, caplet, gelcap, or liquid gel every 8 to 12 hours while symptoms last. For the first dose, you may take 2 tablets, caplets, gelcaps or capsules within the first hour.
  • Do not exceed 2 tablets, caplets, or gelcaps, or liquid gels in any 8- to 12-hour period, and do not exceed 3 tablets, caplets or gelcaps, or liquid gels in a 24-hour period. The smallest effective dose should be used. Drink a full glass of water with each dose.
  • Do not take longer than 10 consecutive days for pain or 3 days for fever, unless directed by a doctor.
What’s the dose for children under 12?
Do not give this product to children under age 12, except under the advice and supervision of a doctor.
How many days can I take Aleve?
Do not take longer than 10 consecutive days for pain or 3 days for fever, unless directed by a doctor.
What are some of Aleve’s possible side effects?
  • Common side effects seen with Aleve are abdominal pain, dizziness, headache, heartburn, nausea and light-headedness. More serious, though rare, effects seen with Aleve include severe allergic reactions. This product contains an NSAID, which may cause severe stomach bleeding.
  • If you have experienced a side effect, you should speak with your healthcare provider about continuing to take Aleve.
  • When taken as directed on the label, Aleve is a safe and effective pain reliever. Since its introduction as an over-the-counter product in 1994, Aleve has been used by millions of people as a safe and effective pain reliever.
Can Aleve cause allergic reactions?
Yes. If you have ever had hives, facial swelling, asthma (wheezing), shock, rash, skin reddening, or blisters after taking a pain reliever or fever reducer, do not take Aleve. You may have a serious reaction. If an allergic reaction occurs on Aleve, stop use and seek medical help right away.
Can Aleve be taken if I have high blood pressure?
Your doctor best understands your overall health. Talk with him or her to determine if Aleve is appropriate for you.
Can Aleve be taken with high blood pressure medication?
Aleve can interact with some blood pressure medications, so talk to your doctor to determine whether Aleve is appropriate for you.
Can Aleve be taken with blood thinners such as Coumadin?
If you are taking any other drug, talk to a doctor before use to determine whether Aleve is appropriate for you.
Can Aleve be taken with other over-the-counter medications or prescription medications?
  • If you are taking any other drug, talk to a doctor or pharmacist before use to determine whether Aleve is appropriate for you.
  • Interactions from using 2 drugs at the same time are possible. (Interactions are the effects that result from using 2 drugs at the same time; one may make the other less effective or cause mild to serious side effects.)
Can Aleve be taken with other over-the-counter pain relievers such as aspirin, Tylenol® or Advil®?
No pain reliever, including Aleve, should be taken while using any of these products, unless directed to do so by your doctor. If you are taking aspirin on a daily basis, check with your doctor before using any other pain relief product.
Can I drink alcoholic beverages (wine, beer or liquor) while I’m taking Aleve?
This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you have 3 or more alcoholic drinks every day while using this product.
Should I take Aleve with food or liquid?
A full glass of water is required. Take with food or milk if an upset stomach occurs.
Is it okay to take Aleve before or after surgery?
Discuss this issue with your doctor to get the answer that’s right for your needs. Only he or she is best qualified to answer this question.
Is it alright to use Aleve while pregnant or nursing?
If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use naproxen sodium during the last 3 months of pregnancy, unless specifically directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery.
Can I take Aleve if I have diabetes?
Speak with your doctor before adding any drug to your current medication(s).
The package says my Aleve has expired – can I still use it?
It is not recommended to use any over the counter product beyond the labeled expiration date. Like all drugs, Aleve can deteriorate over time and not be as effective once it is past its expiration.
Can they be chewed/crushed/cut in half?
While we recommend that the product be swallowed whole with a full glass of water, there is no harm in chewing or crushing the tablet. Regardless of how it is taken, it is recommended that it be taken with a full glass of water. The Liquid Gels should not be cut or crushed and should be swallowed whole with a full glass of water.
What are Aleve Arthritis Caps?
Has the Aleve Arthritis Cap package been approved by the Arthritis Foundation®?
Yes. The Easy Open Arthritis Cap and Soft Grip Arthritis Cap were approved and have received the Arthritis Foundation’s Ease-of-Use Commendation. The Soft Grip Arthritis Cap also passed the strict guidelines and test protocol of the Consumer Product Safety Commission for child-resistant packaging.
Are Aleve bottles recyclable?
  • Yes, our Aleve bottles are HDPE (high-density polyethylene and polystyrene) plastic. If you do wish to recycle the Aleve bottle, it is classified as a mixed plastics code “7.”
  • Our non-arthritis Aleve cap is recyclable and made of polypropylene plastic. It is classified as a code “5.”
  • Our new Aleve Easy Open Arthritis Cap is recyclable and made of polypropylene plastic. It is classified as a mixed plastics code “7.”
Why do some Aleve bottles have a fold-out label?
Some of our bottles have a fold-out label that provides more room to print directions and warnings. The label also uses a larger print size so important information can be more easily read.
What if I have other questions or comments about Aleve?
Aleve encourages you to contact us in the U.S. via email or our toll-free telephone number: 1-800-395-0689.
What is Aleve PM?
Aleve PM is the first and only over-the-counter (OTC) PM product with the 12-hour pain relieving strength of Aleve plus a sleep aid. Each caplet combines the sleep aid, diphenhydramine HCl (25 mg) with the pain reliever naproxen sodium (220 mg), a nonsteroidal anti-inflammatory drug, to provide relief from occasional sleeplessness associated with minor aches and pains. It can help you fall asleep and stay asleep.
What are the active ingredients in Aleve PM?
Each caplet contains naproxen sodium, 220 mg, which can provide up to 12-hours of pain relief, and diphenhydramine HCl, 25 mg, which is a sleep aid.
What is Aleve PM used for?
Aleve PM should be used for: 1) occasional sleeplessness associated with minor aches and pains, and 2) help falling asleep and staying asleep.
How does Aleve PM work?
Aleve PM can help you fall asleep and stay asleep with less pain for a good night’s rest. The naproxen sodium (220 mg) in Aleve PM works by temporarily blocking the body's production of naturally occurring chemicals called prostaglandins. Prostaglandins play a direct role in pain. Naproxen sodium has the strength to provide up to 12 hours of pain relief. The diphenhydramine HCl in Aleve PM acts as a sleep aid.
How is Aleve PM different from regular Aleve?
Aleve PM contains the same pain reliever found in Aleve (naproxen sodium), but also has a sleep aid (diphenhydramine HCl) so you can stay asleep with less pain and have a good night’s rest.
Is Aleve PM an anti-inflammatory?
Each Aleve PM caplet combines the pain reliever naproxen sodium (220 mg), part of a class of drugs known as Nonsteroidal Anti-Inflammatory Drugs (NSAIDs), with the sleep aid diphenhydramine HCl (25 mg). You should consult your doctor if you have questions about whether Aleve PM is right for you.
Is Aleve PM a sleep aid?
Each Aleve PM caplet combines the sleep aid diphenhydramine HCl (25 mg) with the pain reliever naproxen sodium (220 mg) to provide relief from occasional sleeplessness when associated with minor aches and pains. It can help you fall asleep and stay asleep.
Will Aleve PM treat allergy symptoms?
No, Aleve PM is not indicated to treat allergy symptoms. Although Aleve PM contains diphenhydramine HCl, which can be used as both an anti-histamine and a sleep aid, it is indicated as a sleep aid in Aleve PM. Aleve PM should be used according to the labeled directions.
What are the benefits of Aleve PM?
Aleve PM can provide long-lasting relief from occasional sleeplessness associated with back, muscle or minor arthritis pain. Aleve PM is the first and only over-the-counter (OTC) PM product with the 12-hour pain relieving strength of Aleve plus a sleep aid so you can fall asleep easily and wake up with less pain.
Has Aleve PM been found to be safe?
Yes, Aleve PM was found to be safe in clinical trials. Aleve PM is indicated for occasional sleeplessness associated with minor aches and pain. Aleve PM is safe and effective when used as directed.
What is the safety history of the ingredients in Aleve PM?
The two active ingredients in Aleve PM, naproxen sodium and diphenhydramine HCl, have a long history of being safe and effective when used as directed. Naproxen sodium has been used for over 30 years; diphenhydramine HCl has been used for over 60 years.
Is Aleve PM as safe as Aleve?
Both products were approved by the FDA as safe and efficacious when used according to labeled directions.
What are the possible side effects of Aleve PM?
In clinical studies, the most common side effects were nausea, headaches, dizziness, and vomiting. Refer to the Aleve PM drug facts label and use as directed.

As with all NSAIDs, this product contains a stomach bleeding warning and may cause severe stomach bleeding.

As with all NSAIDS, this product contains an allergy warning. Naproxen Sodium may cause a severe allergic reaction, especially in people allergic to aspirin. If an allergic reaction occurs, consumers should stop use and seek medical help right away.

If you have experienced any side effect, you should speak with your healthcare provider about continuing to take Aleve PM. See package labeling for complete information and warnings.
Can/Should Aleve PM be taken with food?
If stomach upset occurs, Aleve PM can be taken with food or milk. If taken with food, the product may take longer to work.
Can you take Aleve with Aleve PM?
Aleve PM should not be taken at the same time as Aleve. In a 24-hour period, you can take Aleve PM at bedtime and one Aleve 12 hours before or after the Aleve PM dose.
Can you take Aleve PM during the day?
It is not recommended to take Aleve PM during the day if you are not planning to sleep, because it contains a sleep aid, which causes drowsiness.
What if you take more Aleve PM caplets than directed within a 24-hour period?
It is not recommended to take more than two caplets within 24 hours.
Taking more than directed can cause serious health problems. In case of overdose, get medical help or contact a Poison Control Center right away.
Is Aleve PM habit-forming?
The FDA has approved Aleve PM as safe and effective when used as directed. Aleve PM contains a non-habit forming sleep-aid, diphenhydramine HCl.
How does Aleve-D work?
Aleve-D contains naproxen sodium and extended release pseudoephedrine. Naproxen sodium is an effective long-acting analgesic that relieves headaches, body aches and pains, and fever that may result from a cold. The pseudoephedrine HCL in Aleve-D is an extended release nasal decongestant and works by promoting sinus drainage, decreasing swelling of the nasal mucosa, and reducing sinus pressure.
How does Aleve-D last up to 12 hours?
Aleve-D lasts up to 12 hours because naproxen sodium is inherently a long-lasting pain reliever and the pseudoephedrine component is specially formulated to provide extended relief for up to 12 hours with just one pill.
Is Aleve-D considered a "non-drowsy" formula?
Yes. Aleve-D does not contain an anti-histamine and is therefore considered to be "non-drowsy."
What are the active ingredients in Aleve-D?
There are two active ingredients: naproxen sodium 220 mg and extended release pseudoephedrine HCL 120 mg.
What is naproxen sodium?
Naproxen sodium is an analgesic and is indicated for the temporary relief of minor aches and pains due to the common cold, for the temporary reduction of fever, and for the relief of other types of mild to moderate pain.
Can Aleve and Aleve-D be taken at the same time?
No, the two products should not be taken at the same time. The total daily limit for naproxen sodium (660 mg) must be observed.
What are the possible side effects of Aleve-D?
  • Common side effects seen with Aleve-D are: dizziness, drowsiness, headache, lightheadedness, nausea, nervousness, palpitations, sleeplessness and vomiting. When side effects of Aleve-D do occur, in most cases, they are minor and do not require medical attention.
  • More serious, though rare effects seen with Aleve-D include severe allergic reactions, gastrointestinal ulcers and gastrointestinal bleeding. If an allergic reaction or bleeding event occurs, stop use and seek medical help right away.
  • If you have experienced any side effect, you should speak with your healthcare provider about continuing to take Aleve-D. See package labeling for complete information and warnings.
Where can I find Aleve-D for purchase?
  • Click here to use the Product Locator tool at BayerCare.com to find an Aleve-D product in a store near you.
  • Aleve-D is available behind the pharmacy counter without a prescription.
What is nasal congestion?
Nasal congestion can result from inflammation of the lining of the nasal passages. It is caused by a swelling of the blood vessels, excess fluid in the tissues, and an increased secretion of mucus.
What causes nasal congestion?
Congestion of the membrane lining of the nasal passages results most commonly from upper respiratory infections caused by a wide variety of viruses, for example the common cold. It may also be caused by pollens and other irritants in the air.
What is sinus pressure?
Pressure in the sinuses results from an accumulation of fluids and a swelling of the blood vessels in the mucus membrane lining of the sinuses.
What is the difference between having a cold and having sinus pressure?
Sinus pressure may be one of the many symptoms of the common cold. In addition to sinus pressure, symptoms of a cold may include coughing, sneezing, nasal congestion, headache, minor body aches and fever.
How long will my cold symptoms last?
A cold usually lasts approximately 7 days. Clinical signs and symptoms vary from person to person and may include: sore throat, sinus pressure, minor body aches, headache, nasal and sinus congestion, and occasionally a slight fever. Treatment should temporarily relieve your cold symptoms.
How can I prevent a cold?
Handwashing is the most effective way to prevent colds. If possible, one should avoid close, prolonged exposure to persons who have colds. Daily diets should include foods such as fresh, dark-colored fruits and vegetables, which are rich in antioxidants that help support the immune system. Viruses causing the cold can survive hours outside the nasal passages on inanimate objects and skin. Therefore, cleaning household surfaces with antiviral disinfectant might help prevent the spread of infection.
Is my cold contagious?
Yes. Colds are caused by more than 200 different viruses. These viruses are spread by person-to-person contact through contaminated secretions on the fingers and hands, and through particles in the air from sneezing and coughing.